How Bovaer® Works: A First-In-Class Methane-Reducing Feed Ingredient

Elanco recently announced the U.S. Food and Drug Administration (FDA) has completed its comprehensive, multi-year review of Bovaer® (3-NOP), a first-in-class methane-reducing feed ingredient, and determined the product meets safety and efficacy requirements for use in lactating dairy cattle.

Bovaer® (3-NOP) is a feed ingredient that suppresses an enzyme in the cow’s rumen that forms methane. As it acts, Bovaer is safely broken down into compounds already naturally present in the rumen, proving that it is safe for the animals, producers and consumers and has been shown to consistently reduce enteric methane emissions in lactating dairy cows about 30%.(1) 

1. Kebreab, E., Bannink, A., Pressman, E. M., Walker, N., Karagiannis, A., van Gastelen, S., & Dijkstra, J. (2023). A meta-analysis of effects of 3-nitrooxypropanol on methane production, yield, and intensity in dairy cattle. Journal of Dairy Science, 106(2), 927–936. https://doi.org/10.3168/jds.2022-22211 based on 60 ppm, 25 kg/d DMI, 30% NDF, and 305 day lactation results in a 31.6% or 1.2 MT reduction